Table 1.
Descriptive statistics by recipient donor obesity (n = 51,556).
| Covariates | Nonobese R | Obese∗ R | p ∗∗ | ||
|---|---|---|---|---|---|
| Nonobese D (n = 26162) | Obese∗ D (n = 8055) | Nonobese D (n = 12295) | Obese D (n = 5044) | ||
| N (%) or mean (SD) | N (%) or mean (SD) | N (%) or mean (SD) | N (%) or mean (SD) | ||
| Male recipient | 17707 (68%) | 6177 (77%) | 7967 (65%) | 3661 (73%) | <0.001 |
|
| |||||
| Recipient age | 53.4 (10.6) | 54.0 (10.0) | 54.3 (8.7) | 54.7 (8.3) | <0.001 |
|
| |||||
| Recipient race | <0.001 | ||||
| White | 18395 (70%) | 5887 (73%) | 9090 (74%) | 3928 (78%) | |
| Black | 2549 (10%) | 794 (10%) | 1096 (9%) | 408 (8%) | |
| Other | 5218 (20%) | 1374 (17%) | 2109 (17%) | 708 (14%) | |
|
| |||||
| Etiology | <0.001 | ||||
| Viral | 7439 (28%) | 2183 (27%) | 3443 (28%) | 1297 (26%) | |
| Cryptogenic | 1446 (6%) | 455 (6%) | 946 (8%) | 398 (8%) | |
| Autoimmune | 3276 (13%) | 881 (11%) | 864 (7%) | 305 (6%) | |
| NASH | 811 (3%) | 257 (3%) | 1258 (10%) | 587 (12%) | |
| Alcoholic | 4442 (17%) | 1575 (20%) | 2093 (17%) | 904 (18%) | |
| HCC | 4897 (19%) | 1681 (21%) | 2338 (19%) | 1072 (21%) | |
| Other | 3850 (15%) | 1021 (13%) | 1351 (11%) | 481 (10%) | |
|
| |||||
| Recipient diabetes | 5565 (22%) | 1772 (22%) | 3671 (30%) | 1526 (31%) | <0.001 |
|
| |||||
| Acute rejection before discharge | 1468 (6%) | 484 (7%) | 670 (6%) | 286 (6%) | 0.588 |
|
| |||||
| PVT at transplantation | 1817 (7%) | 533 (7%) | 1011 (8%) | 396 (8%) | <0.001 |
|
| |||||
| MELD score at LT | 21.4 (10.1) | 21.2 (10.0) | 22.3 (10.2) | 21.5 (9.9) | <0.001 |
|
| |||||
| Recipient BMI | 24.8 (3.2) | 25.3 (3.0) | 34.5 (3.8) | 34.7 (3.8) | <0.001 |
|
| |||||
| Male donor | 15721 (60%) | 4006 (50%) | 7929 (64%) | 2766 (55%) | <0.001 |
|
| |||||
| Donor age | 40.4 (17.7) | 45.5 (14.7) | 41.2 (17.3) | 45.7 (14.8) | <0.001 |
| Donor race | <0.001 | ||||
| White | 17356 (66%) | 5160 (64%) | 8409 (68%) | 3304 (66%) | |
| Black | 4159 (16%) | 1634 (20%) | 1964 (16%) | 1052 (21%) | |
| Other | 4647 (18%) | 1261 (16%) | 1922 (16%) | 688 (14%) | |
|
| |||||
| Donor diabetes | 1976 (8%) | 1440 (18%) | 1002 (8%) | 990 (20%) | <0.001 |
|
| |||||
| Donor hypertension | 7507 (29%) | 4013 (50%) | 3723 (30%) | 2591 (52%) | <0.001 |
|
| |||||
| Donor CMV positive | 17273 (66%) | 5416 (67%) | 8043 (66%) | 3314 (66%) | 0.062 |
|
| |||||
| Donor HBV positive | 1492 (6%) | 444 (6%) | 621 (5%) | 250 (5%) | 0.023 |
|
| |||||
| Donor HCV positive | 920 (4%) | 210 (3%) | 473 (4%) | 107 (2%) | <0.001 |
|
| |||||
| Cold ischemia time | 7.0 (3.4) | 7.1 (3.4) | 7.2 (3.5) | 7.2 (3.5) | <0.001 |
|
| |||||
| Donor creatinine | 1.4 (1.5) | 1.7 (1.8) | 1.5 (1.5) | 1.8 (1.8) | <0.001 |
|
| |||||
| Donor BMI | 24.2 (3.3) | 34.9 (4.9) | 24.6 (3.2) | 35.4 (5.3) | <0.001 |
|
| |||||
| Death after LT | 6470 (25%) | 1913 (24%) | 2836 (23%) | 1166 (23%) | 0.001 |
| Death within 1–30 days | 848 (3%) | 253 (3%) | 440 (4%) | 218 (4%) | <0.001 |
| Death past 30 days, within 1 year | 2175 (9%) | 622 (8%) | 931 (8%) | 372 (8%) | 0.029 |
| Death past 1 year, within 5 years | 2631 (11%) | 815 (11%) | 1114 (10%) | 461 (10%) | 0.004 |
|
| |||||
| Retransplant | 1180 (5%) | 326 (4%) | 571 (5%) | 214 (4%) | 0.179 |
|
| |||||
| Length of hospital stay post-LT | 16.7 (22.5) | 16.1 (21.8) | 16.8 (24.2) | 16.1 (20.4) | 0.046 |
|
| |||||
| Survival time | 1275 (1049) | 1157 (991) | 1235 (1034) | 1137 (995) | <0.001 |
∗Obesity defined as BMI ≥ 30 kg/m2. ∗∗Chi-square test for categorical variables and ANOVA for continuous variables.