Table 3.
Distribution of genotype and alleles frequencies of VDR SNPs in all patients (Behçet's disease and neuro-Behçet's disease) and control subjects.
| Controls n (%) | All patients | p value | |
|---|---|---|---|
| ApaI genotype | |||
| AC | 10 (33.3) | 24 (42.9) | 0.389 |
| AA | 13 (43.3) | 13 (23.2) | 0.053 |
| CC | 7 (23.4) | 19 (33.9) | 0.308 |
| HWE | |||
| χ 2 | 2.80 | 0.989 | |
| p value | 0.0942 | 0.319 | |
|
| |||
| ApaI alleles | |||
| A | 36 (60) | 50 (44.6) | |
| C | 24 (40) | 62 (55.4) | 0.05 |
|
| |||
| TaqI genotype | |||
| CT | 11 (36.7) | 24 (41.4) | 0.669 |
| TT | 13 (43.3) | 27 (46.6) | 0.774 |
| CC | 6 (20) | 7 (12.1) | 0.320 |
| HWE | |||
| χ 2 | 1.511 | 0.213 | |
| p value | 0.218 | 0.643 | |
|
| |||
| TaqI alleles | |||
| C | 23 (38.3) | 38 (32.8) | |
| T | 37 (61.7) | 78 (67.2) | 0.46 |
|
| |||
| FokI genotype | |||
| CT | 12 (40) | 22 (37.9) | 0.85 |
| TT | 15 (50) | 33 (56.9) | 0.538 |
| CC | 3 (10) | 3 (5.2) | 0.394 |
| HWE | |||
| χ 2 | 0.068 | 0.074 | |
| p value | 0.794 | 0.785 | |
|
| |||
| FokI alleles | |||
| T | 42 (70) | 88 (75.8) | |
| C | 18 (30) | 28 (24.2) | 0.40 |
Differences were considered statistically significant at a p value < 0.05.