Table 1.
ESCRT subunits in yeast and mammals Tabular list of ESCRT components in yeast and mammalian cells; in mammalian cells, ESCRT-III components are referred to as CHMPs, due to their identification as Charged Multivesicular Body Proteins [32]/Chromatin Modifying Proteins (CHMPs) [33]
| Complex | Yeast | Mammals |
|---|---|---|
| ESCRT-I | Vps23 | TSG101 |
| Vps28 | VPS28 | |
| Vps37 | VPS37A, VPS37B, VPS37C, VPS37D | |
| Mvb12 | MVB12A, MVB12B, UBAP1 | |
| ESCRT-II | Vps22 | EAP30 |
| Vps25 | EAP20 | |
| Vps36 | EAP45 | |
| ESCRT-III | Did2/Vps46 | CHMP1A, CHMP1B |
| Vps2 | CHMP2A, CHMP2B | |
| Vps24 | CHMP3 | |
| Snf7 | CHMP4A, CHMP4B, CHMP4C | |
| Vps60 | CHMP5 | |
| Vps20 | CHMP6 | |
| Chm7 | CHMP7 | |
| ESCRT associated | Vps4 | VPS4A, VPS4B |
| Vta1 | LIP5 | |
| Bro1 | ALIX, HD-PTP | |
| Ist1 | IST1 | |
| ? | SPASTIN | |