Table 1. List of non-metabolic genes differentially expressed in PV cells hemizygous for Pten.
| Gene | P-value | Fold change | Validation |
|---|---|---|---|
| CD300A | 5.71E-5 | 1.484 | |
| E030006K04RIK | 0.000182 | 1.641 | |
| ANLN | 0.000374 | 0.597 | |
| EPHB4 | 0.000392 | 1.475 | q-RT PCR |
| VLDLR | 0.000577 | 0.730 | |
| BIN1 | 0.000585 | 0.588 | |
| GJA5 | 0.000621 | 1.306 | |
| STMN4 | 0.000661 | 0.544 | |
| EVI1 | 0.000676 | 1.591 | |
| ADRA2C | 0.000683 | 0.707 | |
| 9930117H01RIK | 0.000703 | 1.575 | |
| TGFBR1 | 0.000880 | 0.745 | |
| CEACAM1 | 0.000885 | 1.351 | |
| APOE | 0.000908 | 1.301 | |
| VLDLR | 0.000921 | 0.683 | |
| BCL2L2 | 0.000991 | 0.781 | |
| OLFR6 | 0.000999 | 1.345 |
Criteria for inclusion were a logFC>0.5 and P<0.001 (see ref. 28). Note the increased expression of Ephb4. Real-time quantitative PCR (ddCt-1.84) was used to verify this result.