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. 2016 Sep 15;6:33205. doi: 10.1038/srep33205

Figure 3. Overexpression of STYK1 promotes HCC cell proliferation and tumor growth both in vitro and in vivo.

Figure 3

(A) MTT assay revealed increased cell proliferation of BEL-7402 and SMMC-7721 cells with STYK1 compared to control. (B) Representative images of colony formation of BEL-7402 and SMMC-7721 cells with control vector or STYK1, demonstrating increased colony formation in cells with the STYK1. (C) Representative images of tumor at sacrifice, obtained from mice implanted with BEL-7402 HCC cells with either empty vector or STYK1. (D) Tumor volume and tumor weight curves, demonstrating that tumors derived from BEL-7402 cells with STYK1 vector have significantly greater volumes and weights after 4 weeks than those derived from HCC cells with control vector. (E) Reprehensive IHC staining for Ki67 expression in xenograft tumor tissues from the control vector or STYK1 vector. **P  <  0.01.