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. 2016 Sep 15;6:33205. doi: 10.1038/srep33205

Figure 4. Overexpression of STYK1 increases HCC cell migratory and invasive capacity in vitro and number of pulmonary metastases in vivo.

Figure 4

(A) BEL-7402 HCC cells with STYK1 have significantly increased migratory and invasive capacity compared to cells with control vector. (B) SMMC-7721 HCC cells with STYK1 have significantly increased migratory and invasive capacity compared to cells with control vector. (C) Representative histopathologic images of the lungs demonstrating metastatic nodules are shown in the left panel. Mice implanted with BEL-7402 cells with STYK1 had a significantly larger number of pulmonary metastases than mice implanted with HCC cells with the control vector, as is summarized in the right panel. **P  <  0.01.