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. 2016 Sep 15;6:33205. doi: 10.1038/srep33205

Table 3. Multivariate Analyses of Factors Associated with Overall Survival and Time to Recurrence.

Variable Overall Survival
Time to Recurrence
Hazard ratio (95% CI) P Value Hazard ratio (95% CI) P Value
Tumor size (cm; ≤5 vs. >5) 1.184 (0.680–2.061) NS 1.445 (0.858–2.435) 0.166
Tumor number (single vs. multiple) 1.267 (0.618–2.599) NS    
Vascular invasion (no vs. yes) 1.903 (1.121–3.233) 0.017 1.894 (1.161–3.087) 0.010
STYK1 (high vs. low) 1.987 (1.126–3.507) 0.018 2.059 (1.214–3.493) 0.007

NOTE: Multivariate analysis, Cox proportional hazards regression model.

Abbreviation: 95% CI, 95% confidence interval; AFP, alpha-fetoprotein; NS, not significant (Cox proportional hazards regression model); BCLC, Barcelona Clinic Liver Cancer staging system.