Table 1. Suggestively significant interactions between Y-hg O3e* and SNPs in control and case groups.
Chr | SNPa | MAFb | MAFc | ORSNP | PSNP | ORO3e* | PO3e* | ORinter | Pinter | R2 |
---|---|---|---|---|---|---|---|---|---|---|
2 | rs13017562 | 0.38 | 0.36 | 0.93 | 0.26 | 0.31 | 3.63 × 10−8 | 2.22 | 2.62 × 10−5 | 0.064 |
2 | rs869633 | 0.38 | 0.36 | 0.93 | 0.26 | 0.31 | 3.72 × 10−8 | 2.22 | 2.69 × 10−5 | 0.064 |
2 | rs869632 | 0.38 | 0.36 | 0.94 | 0.29 | 0.32 | 4.69 × 10−8 | 2.18 | 3.68 × 10−5 | 0.063 |
2 | rs815808 | 0.06 | 0.09 | 0.91 | 0.37 | 0.45 | 1.10 × 10−7 | 3.42 | 3.05 × 10−5 | 0.065 |
2 | rs815807 | 0.05 | 0.08 | 0.91 | 0.40 | 0.46 | 2.08 × 10−7 | 3.36 | 6.83 × 10−5 | 0.063 |
2 | rs1723493 | 0.04 | 0.08 | 0.91 | 0.45 | 0.47 | 2.28 × 10−7 | 3.34 | 9.03 × 10−5 | 0.063 |
2 | rs11678378 | 0.44 | 0.43 | 1.00 | 0.99 | 1.12 | 0.560 | 0.46 | 7.63 × 10−5 | 0.063 |
3 | rs17217643 | 0.31 | 0.33 | 0.87 | 0.03 | 0.35 | 5.42 × 10−8 | 2.26 | 5.25 × 10−5 | 0.063 |
3 | rs6774209 | 0.31 | 0.33 | 0.87 | 0.03 | 0.34 | 4.45 × 10−8 | 2.24 | 9.16 × 10−5 | 0.065 |
3 | rs10513814 | 0.19 | 0.20 | 0.86 | 0.07 | 0.41 | 1.08 × 10−7 | 2.30 | 9.75 × 10−5 | 0.062 |
4 | rs17005650 | 0.33 | 0.37 | 1.05 | 0.44 | 0.32 | 5.99 × 10−8 | 2.26 | 3.47 × 10−5 | 0.066 |
5 | rs11135482 | 0.39 | 0.42 | 0.83 | 4.93 × 10−3 | 0.31 | 1.02 × 10−7 | 2.07 | 9.11 × 10−5 | 0.064 |
5 | rs11135484 | 0.39 | 0.43 | 0.80 | 9.09 × 10−4 | 0.31 | 1.56 × 10−7 | 2.07 | 9.89 × 10−5 | 0.065 |
5 | rs12520985 | 0.23 | 0.24 | 1.11 | 0.14 | 0.89 | 0.455 | 0.38 | 7.15 × 10−5 | 0.064 |
5 | rs13181162 | 0.41 | 0.41 | 0.94 | 0.31 | 0.30 | 1.36 × 10−7 | 2.10 | 9.36 × 10−5 | 0.062 |
6 | rs16891417 | 0.09 | 0.06 | 0.91 | 0.44 | 0.49 | 5.41 × 10−7 | 4.52 | 7.07 × 10−5 | 0.063 |
6 | rs3818947 | 0.08 | 0.06 | 0.89 | 0.38 | 0.49 | 5.54 × 10−7 | 4.58 | 6.26 × 10−5 | 0.063 |
6 | rs16891497 | 0.09 | 0.06 | 0.95 | 0.69 | 0.48 | 3.37 × 10−7 | 4.45 | 4.41 × 10−5 | 0.063 |
6 | rs16891501 | 0.09 | 0.06 | 0.86 | 0.25 | 0.49 | 5.48 × 10−7 | 4.23 | 7.95 × 10−5 | 0.062 |
6 | rs9452333 | 0.34 | 0.42 | 1.02 | 0.77 | 1.04 | 0.847 | 0.47 | 9.88 × 10−5 | 0.063 |
7 | rs17139327 | 0.22 | 0.25 | 0.85 | 0.03 | 0.39 | 5.83 × 10−8 | 2.42 | 6.11 × 10−5 | 0.064 |
8 | rs10957317 | 0.15 | 0.15 | 0.86 | 0.08 | 0.42 | 5.78 × 10−8 | 2.79 | 3.05 × 10−5 | 0.063 |
8 | rs12545097 | 0.15 | 0.15 | 0.86 | 0.09 | 0.41 | 3.63 × 10−8 | 2.95 | 1.20 × 10−5 | 0.064 |
8 | rs2385127 | 0.15 | 0.15 | 0.85 | 0.07 | 0.42 | 4.95 × 10−8 | 2.88 | 1.92 × 10−5 | 0.064 |
9 | rs2117103 | 0.18 | 0.19 | 0.93 | 0.34 | 0.40 | 6.98 × 10−8 | 2.37 | 6.17 × 10−5 | 0.063 |
9 | rs1368677 | 0.18 | 0.19 | 0.91 | 0.26 | 0.40 | 6.65 × 10−8 | 2.40 | 4.77 × 10−5 | 0.063 |
9 | rs12555036 | 0.42 | 0.44 | 0.94 | 0.29 | 0.29 | 1.36 × 10−7 | 2.08 | 8.48 × 10−5 | 0.063 |
11 | rs4757259 | 0.30 | 0.26 | 0.86 | 0.04 | 0.38 | 6.48 × 10−8 | 2.40 | 7.45 × 10−5 | 0.063 |
11 | rs4757260 | 0.30 | 0.26 | 0.87 | 0.06 | 0.38 | 6.01 × 10−8 | 2.43 | 5.82 × 10−5 | 0.063 |
11 | rs12286075 | 0.32 | 0.36 | 0.93 | 0.28 | 0.32 | 5.98 × 10−8 | 2.20 | 4.92 × 10−5 | 0.063 |
11 | rs4923182 | 0.42 | 0.46 | 0.98 | 0.70 | 0.24 | 1.12 × 10−8 | 2.51 | 4.12 × 10−6 | 0.067 |
11 | rs4923186 | 0.42 | 0.46 | 0.99 | 0.85 | 0.24 | 1.83 × 10−8 | 2.50 | 5.04 × 10−6 | 0.066 |
12 | rs10841420 | 0.44 | 0.46 | 0.89 | 0.07 | 0.29 | 5.66 × 10−8 | 2.13 | 5.78 × 10−5 | 0.064 |
12 | rs10437774 | 0.43 | 0.44 | 0.90 | 0.09 | 0.31 | 1.05 × 10−7 | 2.09 | 8.46 × 10−5 | 0.063 |
13 | rs9510242 | 0.33 | 0.31 | 1.08 | 0.23 | 0.96 | 0.790 | 0.43 | 8.02 × 10−5 | 0.063 |
15 | rs16968382 | 0.03 | 0.05 | 0.81 | 0.15 | 0.50 | 6.47 × 10−7 | 4.09 | 9.73 × 10−5 | 0.062 |
15 | rs8035166 | 0.36 | 0.35 | 0.85 | 0.01 | 0.34 | 9.47 × 10−8 | 2.15 | 8.29 × 10−5 | 0.063 |
20 | rs12625552 | 0.03 | 0.06 | 0.85 | 0.23 | 0.47 | 2.19 × 10−7 | 3.99 | 2.87 × 10−5 | 0.064 |
OR for odds ratio, P for P value and R2 for goodness of fit of logistic regression models.
aOnly those suggestively significant SNPs with a Pinter < 1 × 10−4 were shown.
bMAF for minor allele frequency in Chinese in 1000 Genomes, cMAF in this study controls.