Table 2.
Cox’s(Baseline) | Cox’s(time-dependent) | JM1 | JM2 | % gain (JM2 vs JM1) | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
t | True | Mean | ESD | Mean | ESD | Mean | ESD | Mean | ESD | True | Estimated |
AUC | |||||||||||
3 | 0.791 | 0.696 | 0.027 | 0.659 | 0.028 | 0.696 | 0.025 | 0.749 | 0.024 | 0.067 | 0.071 |
3.5 | 0.811 | 0.696 | 0.025 | 0.663 | 0.025 | 0.704 | 0.023 | 0.763 | 0.021 | 0.073 | 0.077 |
4 | 0.830 | 0.694 | 0.022 | 0.665 | 0.024 | 0.709 | 0.022 | 0.775 | 0.019 | 0.08 | 0.085 |
4.5 | 0.851 | 0.693 | 0.023 | 0.669 | 0.023 | 0.713 | 0.023 | 0.786 | 0.019 | 0.086 | 0.093 |
5 | 0.871 | 0.694 | 0.024 | 0.675 | 0.024 | 0.717 | 0.022 | 0.798 | 0.019 | 0.093 | 0.102 |
AARD | |||||||||||
3 | 0.434 | 0.288 | 0.048 | 0.231 | 0.048 | 0.288 | 0.045 | 0.368 | 0.050 | 0.184 | 0.217 |
3.5 | 0.465 | 0.285 | 0.044 | 0.233 | 0.044 | 0.299 | 0.043 | 0.388 | 0.041 | 0.191 | 0.229 |
4 | 0.502 | 0.281 | 0.042 | 0.229 | 0.043 | 0.303 | 0.045 | 0.405 | 0.038 | 0.203 | 0.252 |
4.5 | 0.540 | 0.278 | 0.042 | 0.231 | 0.044 | 0.308 | 0.046 | 0.420 | 0.039 | 0.207 | 0.267 |
5 | 0.582 | 0.279 | 0.043 | 0.233 | 0.045 | 0.311 | 0.042 | 0.436 | 0.038 | 0.215 | 0.287 |
MRD | |||||||||||
3 | 0.258 | 0.084 | 0.022 | 0.112 | 0.024 | 0.071 | 0.016 | 0.154 | 0.021 | 0.322 | 0.539 |
3.5 | 0.303 | 0.097 | 0.023 | 0.127 | 0.024 | 0.089 | 0.019 | 0.186 | 0.022 | 0.32 | 0.522 |
4 | 0.337 | 0.103 | 0.023 | 0.127 | 0.023 | 0.103 | 0.020 | 0.211 | 0.022 | 0.32 | 0.512 |
4.5 | 0.362 | 0.104 | 0.023 | 0.119 | 0.022 | 0.114 | 0.021 | 0.230 | 0.022 | 0.32 | 0.504 |
5 | 0.379 | 0.102 | 0.022 | 0.108 | 0.022 | 0.121 | 0.021 | 0.244 | 0.022 | 0.325 | 0.504 |