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. 2016 Sep 15;11:24. doi: 10.1186/s13015-016-0086-4

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Example of four pyro-signal identifications using AdvISER-PYRO-SMQ. The pyro-signals generated by the pyrosequencer are represented by vertical black lines. The contribution of each WT pyro-signal within the dictionary is represented by a dark gray box while the contribution of each somatic mutation signal within the dictionary is represented by a specific color (e.g. light green for Q61K somatic mutation in well A3)