Table 3.
Primary liver diseases and presumptive causes of AKI after operation according to in-hospital mortality
| All patients | Survivors | Non-survivors | P-value | |
|---|---|---|---|---|
| n = 323 | n = 281 | n = 42 | ||
| Primary liver disease | 323 (100) | 281 (100) | 42 (100) | |
| Alcoholic, n (%) | 16 (5) | 12 (4) | 4 (10) | NS (0.254) |
| Hepatitis B, n (%) | 111 (34) | 100 (36) | 11 (26) | NS (0.848) |
| Hepatitis C, n (%) | 31 (10) | 23 (8) | 8 (19) | 0.003 |
| Hepatoma, n (%) | 3 (1) | 3 (1) | 0 (0) | NS (1.000) |
| Alcoholic + hepatitis B, n (%) | 21 (6) | 15 (7) | 2 (5) | NS (1.000) |
| Alcoholic + hepatitis C, n (%) | 5 (2) | 5 (2) | 0 (0) | NS (1.000) |
| Alcoholic + hepatoma, n (%) | 3 (1) | 3 (1) | 0 (0) | NS (1.000) |
| Hepatitis B + hepatitis C, n (%) | 17 (5) | 14 (5) | 3 (7) | NS (0.723) |
| Hepatitis B + hepatoma, n (%) | 49 (15) | 43 (15) | 6 (14) | NS (0.172) |
| Hepatitis C + hepatoma, n (%) | 31 (10) | 29 (10) | 2 (5) | NS (0.134) |
| Alcoholic + hepatitis B + hepatoma, n (%) | 2 (1) | 1 (1) | 1 (2) | NS (0.429) |
| Other causes, n (%)a | 34 (10) | 29 (10) | 5 (12) | NS (0.787) |
| Presence of AKI after transplantation (Post-OP day1) | 125 (39) | 101 (36) | 24 (57) | 0.011 |
| Prerenal type of AKI, n (%) | 2 (1) | 2 (1) | 0 (0) | NS (1.000) |
| Infection related AKI, n (%) | 42 (13) | 31 (11) | 11 (26) | 0.006 |
| Nephrotoxic agent exposure related AKI, n (%) | 6 (2) | 6 (2) | 0 (0) | NS (0.601) |
| Mixed type and other causes of AKI, n (%)b | 75 (23) | 62 (22) | 13 (31) | NS (0.236) |
Values in bold are statistically significant (P-value < 0.05)
Hepatitis C virus infection was independently associated with in-hospital mortality
Presence of infection related AKI on the first day after transplantation was independently associated with in-hospital mortality
aBiliary cirrhosis, biliary sclerosis, autoimmune hepatitis, Wilson’s disease, polycystic liver disease, drugs, and unknown causes
bMultifactor related, ischemia/reperfusion injury, or unknown cause