Table 1.

Inclusion and Exclusion Criteria

Inclusion criteria	Exclusion criteria
• Patients receiving anthracycline or trastuzumab-based chemotherapy. • Histologically confirmed malignancy; • Age > 18 years, and • No contraindication to MRI.	• Physical disability preventing exercise testing or DEXA scan; • Psychiatric disease or disorder precluding informed consent; • Contraindication to anti-cancer therapy, including known heart failure, cardiomyopathy, or baseline LV ejection fraction less than 50 %; • Previous anthracycline or trastuzumab-based therapy; • Previous radiotherapy to thorax.