Table 2.
Incidence Rates of Kaposi's Sarcoma and Non-Hodgkin Lymphoma Among Patients With HIV in Routine Clinical Care
| Time-Updated Patient Characteristics | Incidence Rate (per 100,000 person-years) by Calendar Period | IRR (per increasing calendar year) | P-Trend | ||
|---|---|---|---|---|---|
| 1996-2001 | 2002-2006 | 2007-2011 | |||
| Kaposi's sarcoma | |||||
| Total | 243.7 | 232.2 | 168.1 | 0.95 | .003 |
| ART status | |||||
| No ART | 501.5 | 373.8 | 323.4 | 0.94 | .043 |
| ART < 6 months | 733.8 | 1,040.1 | 795.6 | 1.00 | .999 |
| ART ≥ 6 months | 88.3 | 164.0 | 119.4 | 1.01 | .988 |
| CD4 count (cells/μL) | |||||
| < 200 | 674.2 | 816.7 | 609.7 | 0.98 | .540 |
| 200-349 | 129.2 | 234.2 | 255.6 | 1.03 | .565 |
| 350-499 | 36.7 | 114.0 | 136.7 | 1.05 | .461 |
| ≥ 500 | 46.1 | 36.2 | 61.5 | 1.05 | .528 |
| HIV RNA (copies/mL) | |||||
| > 50,000 | 729.0 | 1,088.9 | 967.8 | 1.01 | .660 |
| 500-50,000 | 141.5 | 166.6 | 356.6 | 1.10 | .037 |
| < 500 | 152.3 | 104.3 | 85.7 | 0.93 | .051 |
| Non-Hodgkin lymphoma | |||||
| Total | 249.6 | 166.6 | 112.9 | 0.92 | < .001 |
| ART status | |||||
| No ART | 200.6 | 186.9 | 202.1 | 0.99 | .902 |
| ART < 6 months | 467.0 | 485.4 | 331.5 | 0.95 | .385 |
| ART ≥ 6 months | 238.4 | 146.9 | 91.0 | 0.90 | < .001 |
| CD4 count (cells/μL) | |||||
| < 200 | 855.7 | 539.0 | 336.4 | 0.93 | .012 |
| 200-349 | 96.9 | 87.8 | 180.4 | 1.04 | .537 |
| 350-499 | 36.7 | 156.7 | 85.9 | 0.98 | .757 |
| ≥ 500 | 23.1 | 63.4 | 67.7 | 1.03 | .644 |
| HIV RNA (copies/mL) | |||||
| > 50,000 | 729.0 | 518.5 | 414.8 | 0.94 | .165 |
| 500-50,000 | 101.1 | 230.6 | 231.8 | 1.05 | .335 |
| < 500 | 228.4 | 83.4 | 78.5 | 0.90 | .004 |
Abbreviations: ART, antiretroviral therapy; IRR, incidence rate ratio.