Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Aug 15;113(35):E5172–E5181. doi: 10.1073/pnas.1606253113

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

PMC Copyright notice

Fig. 2. — Monocyte trafficking in inflamed glomerular capillaries is dependent on CX₃CR1, LFA-1 and Mac-1. The role of surface receptors in monocyte trafficking within inflamed glomerular capillaries was investigated in Cx3cr1^GFP/+ and Cx3cr1^GFP/GFP mice using intravital multiphoton microscopy. (A and B) Monocyte adhesion (Left), and dwell time (Right) were quantified 1–2 h after anti-GBM Ab injection in mice pretreated with either anti-LFA-1 (n = 6) (A), anti-Mac-1 (n = 6) (B), or the respective isotype controls (n = 6 and 4, respectively). (C and D) Contribution of CX₃CR1 to glomerular monocyte patrolling during inflammation. Monocyte adhesion and dwell time are shown for Cx3cr1^GFP/+ (n = 6) and Cx3cr1^GFP/GFP mice (n = 6) 0–1 h (C) or 1–2 h (D) after anti-GBM Ab injection. Data are presented as mean ± SEM; *P < 0.05, ***P < 0.001 vs. corresponding control group.