Fig. 2.

Images of preretinal neovascular complexes excised from adult diabetic patients. Voltages were −104 mV in A, −89 mV in B, and −101 mV in C. Unlike the neovascular complexes of the rodent models, the surgical specimens had extensive fibrosis and had been in eyes that had received laser-induced retinal ablation and, in most cases, anti-vascular endothelial growth factor molecules. Despite these differences, suprahyperpolarization is a bioelectric feature of human, as well as rodent, retinal neovascularization. (Scale bars: 25 µm.)