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p53 methylation at K370 and K382 is dependent on the methyltransferases SMYD2 and PR-Set7. (A) p53 K370me1 immunoprecipitation followed by p53 Western blot analysis in NTera2 cells with control (Ctrl) or SMYD2 knockdown mediated by shRNA. (B) p53 K382me1 immunoprecipitation followed by p53 Western blot analysis in NTera2 cells with control (Ctrl) or PR-Set7 knockdown mediated by shRNA.
