Table 1.
Echocardiographic features of SCA mice
| Measurement (unit) | WT | Berk-SS | P value |
| IVSDd (mm) | 1.04 ± 0.03 | 1.13 ± 0.05 | 0.04 |
| LVPWd (mm) | 0.96 ± 0.03 | 1.15 ± 0.05 | 0.005 |
| LVM (mg) | 112 ± 6 | 201 ± 12 | <0.0001 |
| LVIDd (mm) | 3.67 ± 0.16 | 4.72 ± 0.11 | <0.0001 |
| LVSF (%, vol/vol) | 36 ± 3 | 35 ± 2 | 0.38 |
Berk-SS SCA mice (n = 16; 7–8 mo) compared with age- and gender-matched WT controls (n = 14). Data presented as mean ± SEM. Mann–Whitney U test. IVSDd, end-diastolic interventricular septum thickness; LVPWd, end-diastolic LV posterior wall thickness; LVSF, left ventricular shortening fraction.