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Behaviors of the four-component model at various ea values: (A) ea = 10, (B) ea = 4, and (C) ea = 1. Results of in silico experiments visualizing A in the WT and the presence of clones mutant for EGF, Notch, Dl, and EGF/Dl (ee = 0.2 and ne = ed = 1.0). Phase diagrams showing speed of wave progression, acceleration of wave in Notch clone, and SDs of A and N by changing NP (dt = dc = 0.25 × NP) and EP (ne = ae = EP and ee = 0.2 × EP).
