Table 6.
Comparison of TTK rs151658, BUB1B rs1031963, and BUB1B rs1801376 genotypes between the European population and examined groups of Slovenian population
| Population | N | Genotype counts | P |
|---|---|---|---|
| TTK rs151658 | |||
| EUR | 503 | 97 (C|C) / 246 (C|G) / 160 (G|G) | χ2 = 8.391; P = 0.015 a χ2 = 11.143; P = 0.004 b NS c |
| SI (total)a | 283 | 80 (C|C) / 124 (C|G) / 79 (G|G) | |
| SI (cases)b | 108 | 36 (C|C) / 48 (C|G) / 24 (G|G) | |
| SI (controls)c | 175 | 44 (C|C) / 76 (C|G) / 55 (G|G) | |
| BUB1B rs1031963 | |||
| EUR | 503 | 125 (C|C) / 259 (C|T) / 119 (T|T) | NS d NS e χ2 = 5.715; P = 0.057 f |
| EUR - male | 240 | 56 (C|C) / 124 (C|T) / 60 (T|T) | _ c _ d χ2 = 6.348; P = 0.042 f |
| SI (total)d | 280 | 80 (C|C) / 143 (C|T) / 57 (T|T) | |
| SI (cases - female)e | 36 | 6 (C|C) / 23 (C|T) / 7 (T|T) | |
| SI (cases - male)f | 65 | 25 (C|C) / 29 (C|T) / 11 (T|T) | |
| BUB1B rs1801376 | |||
| EUR | 503 | 240 (A|A) / 217 (A|G) / 46 (G|G) | NS g F = 6.569; P = 0.034 h NS 1 |
| EUR - female | 263 | 135 (A|A) / 109 (A|G) / 19 (G|G) | _ g F = 8.277; P = 0.014 h _ i |
| SI (total)g | 279 | 136 (A|A) / 118 (A|G) / 25 (G|G) | |
| SI (cases - female)h | 40 | 11 (A|A) / 25 (A|G) / 4 (G|G) | |
| SI (cases - male)i | 68 | 36 (A|A) / 24 (A|G) / 8 (G|G) |
EUR = European population; F = Fisher statistics; SI (cases) = gastric cancer patients; SI (controls) = control population; SI (total) = combined populations of patients and controls; χ2 = chi-square statistics; superscript letters indicate comparisons between European population and Slovenian populations