Figure 2.
A) WT mice 12–18 wk old maintained on LPD for 2 wk become hypophosphatemic. Mice received a bolus of 30 μmol Pi (Pi-Inf1), 60 μmol (Pi-Inf2), and saline for control group (NaCl-Inf) while in the magnet. B) VATP determined by ST-[31P]MRS was reduced in LPD mice, was increased in these animals after Pi-Inf1, and further increased after Pi-Inf2 compared with NaCl-infused mice. See Fig. 1 and Table 1 for composition of LPD and regular chow (RC). All data are means ± sem; n = 5–8 in each diet group. *P < 0.05, **P < 0.01 by double-sided Student’s t test.