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. 2016 Jun 23;30(10):3378–3387. doi: 10.1096/fj.201600473R

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This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Muscle P_i concentration and V_ATP are positively correlated. Shown is a regression analysis of muscle P_i and V_ATP obtained in WT mice, NaPi2a^−/− mice, and NaPi2a^−/− mice after continuous P_i infusion (A), in the LPD model before and after P_i infusion (B), and in the patient with hypophosphatemic rickets (C). P_i infusion (P_i-Inf) in panels A, B and oral phosphate supplementation after 5 (Rx1) and 8 (Rx2) mo improves V_ATP in all 3 models. Shown are individual animals with regression lines for each treatment group. Pooled regression analysis of all treatment groups was significant with **P < 0.01 in each panel.