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. 2016 Jun 23;30(10):3378–3387. doi: 10.1096/fj.201600473R

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This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — An individual with hypophosphatemic rickets has reduced V_ATP. A) Serum P_i was measured before and again after restoration of hypophosphatemia after a total of 8 mo (Rx2) oral phosphate supplementation with 500 mg KPhos MF 3 times/d, which comprised a total daily dose of 1500 mg. B) V_ATP was measured before, after 5 mo (Rx1), and again after a total of 8 mo (Rx2) treatment. The patient had reduced V_ATP measured by ST-[³¹P]MRS before treatment compared with 5 healthy controls, but V_ATP was restored after 8 mo treatment. All data are means ± sem; n = 5 in the control group. *P < 0.01 by double-sided Student’s t test.