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. 2016 Jun 30;30(10):3501–3514. doi: 10.1096/fj.201600603R

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This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — HRG expression in B. malayi adult females (AF) and mf in response to heme. A) FPKM values show expression of BmHRG-1 is significantly down-regulated (q ≤ 0.01) in the presence of heme in B. malayi adult females (black bars) and mf (gray bars). At every heme concentration tested, BmHRG-1 expression is significantly higher (q ≤ 0.01) in mf (gray bars, uppercase letters) than female worms (black bars, lowercase letters) (note difference in y-axis scales). B) BmHRG-2 expression is significantly down-regulated (q ≤ 0.01) in mf at high (100 μM) heme concentrations. C) BmMRP-5 expression is significantly down-regulated (q ≤ 0.01) in adult female B. malayi at 20 μM heme and above.