. 2016 Jun 20;30(10):3285–3295. doi: 10.1096/fj.201500079R

TABLE 2.

Open probability for slow and fast gating for hClC-1 WT, T335N, and WT + T335N channels in high-chloride solution

ClC-1	V_0.5 P_o^slow[mV (k)]	P_min^slow	V_0.5 P_o^fast[mV (k)]	P_min^fast	Cells (n)
WT	−79 ± 2 (31 ± 1)	0.69 ± 0.03	−87 ± 1 (27 ± 1)	0.64 ± 0.04	10
T335N	90 ± 7 (31 ± 3)*	0.78 ± 0.05	—	0.89 ± 0.07	7
WT + T335N	−40 ± 4 (58 ± 3)*	0.53 ± 0.03	−76 ± 1 (18 ± 1)	0.72 ± 0.02	11

Data are means ± sem of the indicated number of cells. V_0.5, half maximal activation potential; k, slope factor; P_min, minimal value of P_o measured at −90 mV; P_o^fast, open probability of the fast gate; P_o^slow, open probability of the slow gate. *P < 0.05 compared with WT.