Table 2.
3rd generation EGFR TKIs in development
| T790M Specific EGFRm TKI | Current Clinical Status | Comments |
|---|---|---|
| Rociletinib | Phase I and II, III soon | Breakthrough Therapy designation |
| AZD 9291 | Phase II and III | Breakthrough Therapy designation |
| EGF 816 | Phase I/II | |
| Astellas 8273 | Phase I/II | |
| AZD 3759 | Phase I | |
| HM 61713 | Phase I |