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. Author manuscript; available in PMC: 2017 Sep 13.
Published in final edited form as: Cell Metab. 2016 Sep 13;24(3):420–433. doi: 10.1016/j.cmet.2016.08.005

Figure 2. UCP-1 Promoter Driven Cx43 Deletion Does Not Affect BAT Physiology and Thermal Adaptation to the Cold.

Figure 2

A. Schematic of the mouse model. B. Representative confocal images of anti-Cx43 immunofluorescence staining. Scale bar = 25 μm. C. Quantification of Cx43 fluorescent signals (n = 8). D. Trichrome staining of BAT from mice housed at room temperature. Scale bar = 50 μm. E. Acute cold tolerance test (n = 5–6). F. Repeat acute cold tolerance test of the mice previously exposed to the cold for 3 weeks (n = 5–6). G. Trichrome staining of BAT from mice exposed to the cold for 3 weeks. Scale bar = 50 μm. H. Body temperature change during the chronic cold exposure (n = 5–6). I. Body weight gain during 3-week cold exposure (n = 5–6). Results are shown as mean ± SEM, *p < 0.05.