Table 3.
Fatty acid derivatives in adipose tissue of non-tumor bearing mice after 6 weeks EPA+DHA supplementation.
| Adipose Tissue (ng/mg protein) |
Control (n = 3) |
Control + EPA+DHA (n = 3) |
DIO (n = 3) |
DIO + EPA+DHA (n = 3) |
|---|---|---|---|---|
| 6ketoPGF1α | 148 ± 58 | 144 ± 33 | 211 ± 103 | 47.6 ± 47 |
| TXB2 | 6.7 ± 1.5 | 5.4 ± 2.2 | 10.0 ± 5.3 | 4.2 ± 4.2 |
| PGF2α | 11.3 ± 3.5 | 8.7 ± 2.7 | 22.8 ± 11.0 | 4.4 ± 3.5 |
| PGE2 | 35.8 ± 9.9 | 31.3 ± 6.6 | 51.4 ± 34.5 | 9.3 ± 9.2 |
| PGD2 | 47 ± 22 | 37 ± 11 | 199 ± 92 | 113 ± 106 |
| 13HODE | 973 ± 456 | 648 ± 123 | 1175 ± 268 | 769 ± 542 |
| 15HETE | 171 ± 61 | 85 ± 5 | 159 ± 39 | 84 ± 62 |
| 12HETE | 753 ± 216 | 400 ± 72 | 776 ± 158 | 320 ± 230 |
| 5HETE | 11.0 ± 1.2 | 8.6 ± 3.1 | 15.6 ± 3.7 | 18.8 ± 12.6 |
| 18-HEPE | 0.16 ± 0.08a | 2.34 ± 0.44b | 0.79 ± 0.22b | 7.46 ± 6.32b |
| PGE3 | 0.29 ± 0.06a | 3.35 ± 0.94b | 0.73 ± 0.47 | 1.07 ± 0.60 |
6-ketoPGF1α, 6-keto prostaglandin F1α; TXB2, thromboxane B2; PGE3, prostaglandin E3; PGF2α, prostaglandin F2α; PGE2, prostaglandin E2; PGD2, prostaglandin D2; 13HODE, 13-hydroxyoctadecadienoic acid; 15HETE, 15-hydroxyeicosatetraenoic acid; 12HETE, 12-hydroxyeicosatetraenoic acid; 5HETE, 5-hydroxyeicosatetraenoic acid; 18HEPE, 18-hydroxyeicosapentaenoic acid. Statistically significant (P≤0.05) differences are indicated by different letters, e.g., a group designated with is a different than a group designated with b; but two groups with b are not different.