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. Author manuscript; available in PMC: 2016 Sep 15.
Published in final edited form as: Cancer Prev Res (Phila). 2015 Jun 22;8(9):796–806. doi: 10.1158/1940-6207.CAPR-15-0018

Table 3.

Fatty acid derivatives in adipose tissue of non-tumor bearing mice after 6 weeks EPA+DHA supplementation.

Adipose Tissue
(ng/mg protein)
Control

(n = 3)
Control +
EPA+DHA
(n = 3)
DIO

(n = 3)
DIO +
EPA+DHA
(n = 3)
6ketoPGF1α 148 ± 58 144 ± 33 211 ± 103 47.6 ± 47
TXB2 6.7 ± 1.5 5.4 ± 2.2 10.0 ± 5.3 4.2 ± 4.2
PGF2α 11.3 ± 3.5 8.7 ± 2.7 22.8 ± 11.0 4.4 ± 3.5
PGE2 35.8 ± 9.9 31.3 ± 6.6 51.4 ± 34.5 9.3 ± 9.2
PGD2 47 ± 22 37 ± 11 199 ± 92 113 ± 106
13HODE 973 ± 456 648 ± 123 1175 ± 268 769 ± 542
15HETE 171 ± 61 85 ± 5 159 ± 39 84 ± 62
12HETE 753 ± 216 400 ± 72 776 ± 158 320 ± 230
5HETE 11.0 ± 1.2 8.6 ± 3.1 15.6 ± 3.7 18.8 ± 12.6
18-HEPE 0.16 ± 0.08a 2.34 ± 0.44b 0.79 ± 0.22b 7.46 ± 6.32b
PGE3 0.29 ± 0.06a 3.35 ± 0.94b 0.73 ± 0.47 1.07 ± 0.60

6-ketoPGF1α, 6-keto prostaglandin F1α; TXB2, thromboxane B2; PGE3, prostaglandin E3; PGF2α, prostaglandin F2α; PGE2, prostaglandin E2; PGD2, prostaglandin D2; 13HODE, 13-hydroxyoctadecadienoic acid; 15HETE, 15-hydroxyeicosatetraenoic acid; 12HETE, 12-hydroxyeicosatetraenoic acid; 5HETE, 5-hydroxyeicosatetraenoic acid; 18HEPE, 18-hydroxyeicosapentaenoic acid. Statistically significant (P≤0.05) differences are indicated by different letters, e.g., a group designated with is a different than a group designated with b; but two groups with b are not different.