Fig 3. Time-dependent changes of plasma IL6 and TNFα levels after endotoxin-injection in adult male and female mice.

IL10-/- mice at 9–10 weeks old were given LPS injection at 100 EU/kg body weight. Different sets of mice were used for experiments at different time points. (A) IL6 and (B) TNFα plasma values shown are mean±SD of n = 4–6 mice in each group. Student’s t-test was used to determine the effect of gender. *: significantly different at p<0.05.