Table 1. Functional MRI parameters after isogenic and allogenic ktx and in control animals.
| Control | Isogenic ktx | Allogenic ktx | |||
|---|---|---|---|---|---|
| d1 | d6 | d1 | d6 | ||
| ADC cortex, *10-3 mm2/s | 1.593 ± 0.120 | 1.586 ± 0.171 | 1.468 ± 0.189 | 1.381 ± 0.383 | 0.936 ± 0.197***,## |
| ADC medulla, *10-3 mm2/s | 1.690 ± 0.142 | 1.673 ± 0.139 | 1.567 ± 0.229 | 1.297 ± 0.402* | 1.083 ± 0.192***,# |
| T2 cortex, ms | 38.3 ± 2.0 | 50.6 ± 4.4*** | 49.2 ± 7.4*** | 47.3 ±4.7*** | 46.0 ± 3.1*** |
| T2 OSOM, ms | 36.2 ± 2.1 | 51.8 ± 6.0*** | 49.0 ± 8.5*** | 50.9 ± 6.9*** | 48.7 ± 5.6*** |
| T2 ISOM, ms | 47.0 ± 5.1 | 62.5 ± 9.1*** | 58.4 ± 12.0* | 51.9 ± 10.4# | 46.7 ± 7.7# |
| T2 difference, ms | 8.7 ± 3.4 | 11.9 ± 6.2 | 9.1 ± 5.3 | 4.6 ± 9.3# | 0.6 ± 6.7**,# |
Significant differences compared to control kidney after adjustment for multiple comparisons with the Dunn’s test are indicated with
*p<0.05,
**p<0.01,
***p<0.001.
Significant differences of allografts compared to isografts are indicated with
#p<0.05,
##p<0.01.
MRI data of each individual animal is provided in S1 Table. T2 difference represents the difference between T2-relaxation time in inner stripe of the outer medulla (ISOM) and the renal cortex.