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. 2016 Sep 15;11(9):e0162705. doi: 10.1371/journal.pone.0162705

Table 2. Diagnostic accuracy of functional MRI parameters to discriminate allografts with acute rejection from isografts without rejection.

Diagnostic parameter AUC [95% CI] Youden selected threshold Sensitivity at threshold Specificity at threshold Youden index at threshold
ADC cortex 0.97 [0.90;1] 1.315*10-3 mm2/s 89% 100% 89%
ADC outer medulla 0.92 [0.77;1] 1.423*10-3 mm2/s 89% 100% 89%
T2 cortex 0.64 [0.35;0.92] 47.2 ms 56% 99% 55%
T2 OSOM 0.52 [023;0.80] 55.9 ms 33% 99% 32%
T2 ISOM 0.80 [0.59;1] 52.4 ms 60% 78% 82%
T2 difference 0.85 [0.67;1] 8.7 ms 67% 99% 66%

The diagnostic accuracies to discriminate allografts with acute rejection from isografts without rejection by functional MRI at day six after transplantation are given

ADC = apparent diffusion coefficient, AUC = area under the curve, CI = confidence interval, ISOM = inner stripe of the outer medulla, OSOM = outer stripe of the outer medulla.