Table 2. Diagnostic accuracy of functional MRI parameters to discriminate allografts with acute rejection from isografts without rejection.
Diagnostic parameter | AUC [95% CI] | Youden selected threshold | Sensitivity at threshold | Specificity at threshold | Youden index at threshold |
---|---|---|---|---|---|
ADC cortex | 0.97 [0.90;1] | 1.315*10-3 mm2/s | 89% | 100% | 89% |
ADC outer medulla | 0.92 [0.77;1] | 1.423*10-3 mm2/s | 89% | 100% | 89% |
T2 cortex | 0.64 [0.35;0.92] | 47.2 ms | 56% | 99% | 55% |
T2 OSOM | 0.52 [023;0.80] | 55.9 ms | 33% | 99% | 32% |
T2 ISOM | 0.80 [0.59;1] | 52.4 ms | 60% | 78% | 82% |
T2 difference | 0.85 [0.67;1] | 8.7 ms | 67% | 99% | 66% |
The diagnostic accuracies to discriminate allografts with acute rejection from isografts without rejection by functional MRI at day six after transplantation are given
ADC = apparent diffusion coefficient, AUC = area under the curve, CI = confidence interval, ISOM = inner stripe of the outer medulla, OSOM = outer stripe of the outer medulla.