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. 2016 Sep 15;12(9):e1005879. doi: 10.1371/journal.ppat.1005879

Fig 2. SIVsmmFTq infection of RMs can be completely controlled with conventional antiretroviral therapy (ART).

Fig 2

(a) Comparative dynamics of viral replication between RMs in the control group (black symbols and lines) and the RMs receiving a combination ART (PMPA + FTC + L-870812) for a duration of >9 months (treated animals are color-coded, as shown in the legend). (b) Comparison of the changes in peripheral CD4+ T cells between naïve RM controls (black lines and symbols) and RMs receiving ART (red lines and symbols). (c) Comparison of the changes in the frequency of immune activation of peripheral CD4+ and CD8+ T cells between naïve RM controls (black lines and symbols) and RMs receiving ART (red lines and symbols). Duration of ART highlighted in the graphs. The limit of detection (LOD) for the viral load assay is depicted (a) and ranged between 5 and 30 copies/ml depending on the sample availability. In Figs b and c, the lines represent the average values for the monkeys in the groups, and the bars represent the standard errors of the means (sem).