Fig 6. Novel viral perturbations of the innate immunity network reveal new cancer etiologies.

In this network, nodes represent viruses (squares), cancer types (hexagons), and genes (circles). Edges represent virus-host interactions (solid red arrows), cancer-gene associations (striped red arrows), and innate immunity protein-protein interactions (solid gray lines). Various cancer types represented are abbreviated as follows: breast invasive carcinoma (BRCA), bladder urothelial carcinoma (BLCA), colon adenocarcinoma (COAD), diffuse large B-cell lymphoma (DLBCL), glioblastoma multiforme (GBM), head and neck squamous cell carcinoma (HNSC), acute myeloid leukemia (LAML), kidney renal clear cell carcinoma (KIRC), lung adenocarcinoma (LUAD), multiple myeloma (MM), and uterine corpus endometrial carcinoma (UCEC). Detailed data are provided in S5 Table.