Fig 3. RelA stimulates BECN1 expression and the induction of autophagy in LPLI-exposed oral cancer cells.

OECM-1 or Ca9-22 cells stably harboring scramble shRNA or shRNA against RelA were irradiated with (+) or without (-) LPLI (810 nm, 60 J/cm²) and recovered for 24 h. (A) The recovered cells were harvested for immunoblotting to determine protein levels of RelA, BECN1, and MAP1LC3. The protein levels for (B) RelA and (C) BECN1, and (D) the MAP1LC3-II/I ratio were quantified using ACTB as a normalization control. The results are expressed as the mean ± SEM from three independent experiments.