Table 2.

The optimization of the conversion of propargyl alcohols to carbonyl analogous using Pd₁₂₈₉L₁₆₄ catalysts at 25 °C: the effects of temperature, H₂ molar equivalents, and the substrates^a

					Catalysis yields (%)b
Entry	Propargyl alcohol	R1	R2	mmol H2	Semi-hydrogenation	Full-hydrogenation	Tandem reaction	TOFc
1	2-propyn-1-ol	H	H	10	0	42	58	290
2	2-propyn-1-ol	H	H	2	0	30	70	350
3	3-butyn-2-ol	CH3	H	2	0	20	76	380
4	2-butyn-1-ol	H	CH3	2	43	13	41	205
5	3-phenyl-2-propyn-1-ol	H	Ph	2	24	1	39	195

^aReaction condition: 50 µL of propargyl alcohol; 5 mol% Pd, 2 mL CDCl₃; 4 h.

^bYields were determined by ¹H NMR.

^cInitial TOFs are based on the mole isomerized per mole Pd atoms per hour.