Figure 1.

Architecture of the adult stomach and the organization of corpus and antral units. (A) The adult human stomach is composed entirely of glandular epithelium (blue, red), whereas (B) the adult rodent stomach contains a squamous-epithelium–lined forestomach (green), in addition to a glandular stomach. (C) Adult corpus units contain pit/foveolar cells (purple), isthmal stem cells (white), parietal cells (blue), mucous neck cells (green), endocrine cells (light blue), and chief cells (red). Cells transitioning from neck to chief cells are indicated in yellow. (D) Antral units primarily contain pit/fovelar cells (light purple), proliferative isthmal stem cells (white), basal gland cells (light green) similar to mucous neck cells with a hint of chief cell differentiation, and endocrine cells (grey). Note that up to half of human antral gastric units also contain parietal cells (not shown).