FIGURE 2:

Centrosome positioning by pulling forces. (A, B) Top, snapshot after 400 s of a centrosome simulated in different geometries: ellipse, rectangle, equilateral triangle, acute isosceles triangles, and isosceles triangle whose base is the longest side. Dyneins are shown in green, MTs in black, and the centrosome in gray. Motors are distributed (A) cytoplasmically or (B) cortically. Bottom, trajectories of centrosomes in 15 simulations for each geometry. Centrosome position is indicated by colored points, from blue (0 s) to red (400 s), in the trajectory plots. The gray area is the area covered by motors. Black dot indicates the center of gravity of the shape. (C) Left, box plot of the distance of the centrosome to the center of gravity after 400 s for each geometry for cytoplasmic and cortical distributions (full and empty boxes, respectively). Right, strip chart of the final speed of the centrosome in the simulations for all geometries for cytoplasmic and cortical distributions (full and empty triangles, respectively).