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. 2016 Sep 15;27(18):2867–2878. doi: 10.1091/mbc.E16-04-0209

FIGURE 1:

FIGURE 1:

Schematic representation of endosomal retrieval pathways. Trafficking routes of the transferrin receptor (TfR), mannose 6-phosphate receptor (MPR), and Shiga toxin B subunit (STxB) through various compartments of the endomembrane system. The sites of action of the GARP and EARP complexes are indicated, as is the deduced functional localization of TSSC1. MVB, multivesicular body; PM, plasma membrane; RE, recycling endosome; TGN, trans-Golgi network.