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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Mol Cancer Res. 2016 Jun 3;14(9):849–858. doi: 10.1158/1541-7786.MCR-16-0084

Figure 1.

Figure 1

SIX1 localization in controls and following neonatal estrogenic chemical exposure. A. Representative SIX1 immunolabeling in a control adult female mouse reproductive tract at 6 months of age. Arrowhead indicates squamocolumnar junction (SCJ). B. Appearance and expansion of SIX1 immunolabeled cells in mouse endometrium following neonatal GEN or DES exposure at PND5 or 6 months of age. Arrowhead indicates SIX1-positive columnar cells and asterisk indicates SIX1-positive basal-type cells underlying the glandular epithelium. Arrow indicates large SIX1-positive basal-type cell that appears to be traversing the basement membrane. Representative images were taken at an objective magnification of 60× (PND 5) or 40× (6 months of age).