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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Mol Cancer Res. 2016 Jun 3;14(9):869–882. doi: 10.1158/1541-7786.MCR-16-0007

Figure 8. shFAK expression reduces metastatic tumor burden.

Figure 8

Mice were injected with 8505C cells expressing either scrambled shRNA or shFAK. (A) Bioluminescence detection monitored metastatic progression over time. Results shown are mean bioluminescence signal (photons/second) per group ± SEM at the indicated time points. (Total metastatic burden: scrambled group = 1.72×1010 ± 1.29×1010 p/s; shFAK = 8.31×108 ± 2.77×108 p/s (p≤0.001; ANOVA)). (B) Representative bioluminescence images show 1 minute after injection to demonstrate dissemination through the body. Ventral and dorsal images are shown for representative mice at day 42.