Table 4.
Predictors of mortality in peritoneal dialysis patients: univariate and multivariate Cox regression analysis
| Variables | Univariate Cox regression analysis |
Multivariate Cox regression analysis∗ |
||||
|---|---|---|---|---|---|---|
| Hazard ratio | 95% CI | P | Hazard ratio | 95% CI | P | |
| Age (≥ 65 y) | 3.08 | 1.04–1.09 | < 0.001 | – | – | |
| Diabetes | 4.15 | 2.27–7.59 | < 0.001 | 4.02 | 2.10–7.71 | < 0.001 |
| CVD | 3.75 | 2.13–6.61 | < 0.001 | 3.43 | 1.88–6.24 | < 0.001 |
| SGA score | < 0.001 | – | – | |||
| Normal | 1 | |||||
| Mild to moderate | 2.56 | 1.46–4.48 | 0.001 | |||
| Severe | 13.29 | 3.77–46.84 | < 0.001 | |||
| Serum creatinine (mg/dL) | 0.96 | 0.88–1.05 | 0.329 | – | – | – |
| Total cholesterol (mg/dL) | 1.00 | 0.99–1.00 | 0.163 | – | – | – |
| Albumin (g/dL) | 0.63 | 0.32–1.24 | 0.184 | – | – | – |
| Prealbumin (< 40 mg/dL) | 3.42 | 1.72–6.81 | < 0.001 | 2.30 | 1.14–4.64 | 0.020 |
| %LBM | 0.97 | 0.95–0.99 | 0.008 | – | – | – |
| UF volume | 1.00 | 1.00–1.00 | 0.245 | – | – | – |
| RRF (mL/min) | 0.99 | 0.89–1.09 | 0.777 | – | – | – |
| hs-CRP ≥ 1 mg/dL | 1.92 | 1.05–3.51 | 0.034 | 2.11 | 1.12–3.97 | 0.021 |
| Transferrin (mg/dL) | 1.00 | 0.99–1.00 | 0.504 | – | – | – |
| nPCR (g/kg/d) | 1.63 | 0.63–4.20 | 0.314 | – | – | – |
CI, confidence interval; CVD, cardiovascular disease; hs-CRP, high-sensitivity C-reactive protein; %LBM, percent lean body mass; nPCR, normalized protein catabolic rate; RRF, residual renal function; SGA, subjective global assessment; UF, ultrafiltration.
∗
P values were calculated by multivariate Cox proportional regression analysis using the backward conditional method.