Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Sep 16;7:361. doi: 10.3389/fimmu.2016.00361

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Jalapothu, Boieri, Crossland, Shah, Butt, Norden, Dressel, Dickinson and Inngjerdingen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

miRNA expression signature in lung during aGvHD. (A) Volcano plot showing the relationship between fold change and significance between the two groups. The horizontal dashed line indicates cutoff for significance p < 0.05 (−log10 p-value >1.3) and the vertical lines for fold change ≥1.5/≤−1.5. (B) Heatmap showing unsupervised hierarchical clustering of differentially expressed miRNAs in lung between control (n = 3) and aGvHD (n = 3) animals. Each column represents an individual rat. Relative fold change is indicated by the color scale (red: high; blue: low). (C) qRT-PCR analysis of miRNA expression in lung of control (n = 6) or aGvHD (n = 6) rats. Samples were normalized to endogenous controls and expression levels reported as log of 2^−ΔΔCt ± SD. Significance was calculated using the Student’s t-test (two-tailed) with Welch’s correction.