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. 2016 Sep 8;7:12731. doi: 10.1038/ncomms12731

Figure 3. A significant proportion of cell-associated HIV-1 RNA is defective.

Figure 3

The percentage of defective virus detected in CD4+ T cells collected from HIV-infected participants on ART before, during and following administration of panobinostat (baseline DNA n=14, RNA n=7; on HDACi DNA n=15, RNA n=9; post HDACi DNA n=14, RNA n=6) or vorinostat (baseline DNA n=14, RNA n=5; on HDACi DNA n=15, RNA n=6; post HDACi DNA n=14, RNA n=3). Each data point represents the group mean, and the error bars represent the s.e.m. *P≤0.05, **P≤0.01. The Wilcoxon signed rank test was used to generate the P values.