Table 1. In vitro susceptibilities of 16 C. difficile isolates.
Cmpd | MIC50 | MIC90 | MIC Range |
---|---|---|---|
Closantel | 0.25 | 0.25 | 0.13–1 |
Rafoxanide | 0.06 | 0.13 | 0.03–0.13 |
Niclosamide | 1 | 2 | 0.5–4 |
Oxyclozanide | 1 | 1 | 0.5–2 |
Metronidazole | 0.25 | 0.25 | 0.13–0.25 |
Vancomycin | 1 | 2 | 0.5–2 |
Abbreviations: MIC, minimum inhibitory concentration; MIC50 and MIC90, MIC at which 50% and 90% of the isolates are inhibited. All MIC values are expressed in μg/mL (n = 2).