Table 2. MIC values of salicylanilide analogues against C. difficile strains 630 and 4118.
Compound | MIC | |
---|---|---|
C. difficile 630 | C. difficile 4118 | |
5a | 0.5 | 1 |
5b | >32 | >32 |
5c | >32 | >32 |
5d | >32 | >32 |
5e | 0.13 | 0.13 |
5f | 0.13 | 0.25 |
5g | 0.13 | 0.25 |
5h | >32 | >32 |
5i | >32 | >32 |
6a | 0.5 | 0.5 |
6b | >32 | >32 |
6c | >32 | >32 |
7a | 0.5 | 1 |
7b | 0.25 | 0.5 |
7c | 8 | 8 |
7d | 0.13 | 0.25 |
7e | 0.25 | 0.5 |
7f | 2 | 2 |
7g | 1 | 1 |
7h | 0.25 | 0.5 |
7i | 0.25 | 0.5 |
8 | 0.03 | 0.06 |
All minimum inhibitory concentration (MIC) values are expressed in μg/mL (n = 2).