Table 3. In vitro activity against C. difficile strain 4118.
Cmpd | MIC | MBClog | MBCstat |
---|---|---|---|
Closantel | 0.25 | 2 | 4 |
Rafoxanide | 0.13 | 0.5 | 1 |
8 | 0.06 | 0.25 | 1 |
Metronidazole | 0.25 | >32 | >32 |
Vancomycin | 2 | 8 | >32 |
Abbreviations: MIC, minimum inhibitory concentration; MBClog, minimum bactericidal concentration for logarithmic-phase cells; MBCstat, minimum bactericidal concentration for stationary-phase cells. All MIC and MBC values are expressed in μg/mL (n = 2).