FIGURE 8.
Hem25p deficiency influences mitochondrial content of heme and cytochromes. Mitochondrial heme level (A) and cytochrome aa3, b-type, and c-type content (B) were measured by spectrophotometry in mitochondria extracted from the wild-type (open bars), hem25Δ (solid bars), and hem25Δ strain transformed with the HEM25-pYES2 plasmid (gray bars) or with SLC25A38-pYES2 plasmid (hatched bars). Data represent the means ± S.D. of at least five independent experiments. *, p < 0.005 versus wild-type cells; §, p < 0.005 versus hem25Δ cells.