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Scheme of an adhered GUV. Shown is a schematic drawing (top images) and corresponding SDCLM images (bottom images) of a GUV on an avidin-coated surface before and after adhesion. Without adhesion, the GUV geometry can be approximated as a sphere (radius Rv). After adhesion, a spherical cap with a radius of Rad and a circular contact area (with a radius of Ri) is formed. Scale bars: 10 μm.
