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. 2016 Sep 16;6:33664. doi: 10.1038/srep33664

Table 3. Hazard ratios (95% CI) for ischemic stroke according to sleep duration.

  Sleep duration
<6 h 6–8 h >8 h
Cases (%) 210 (3.16) 2240 (2.58) 54 (3.39)
 Model 1 0.94 (0.82–1.08) reference 1.30 (0.99–1.70)
 Model 2 0.92 (0.80–1.07) reference 1.29 (0.98–1.69)
 Model 3§ 0.89 (0.77–1.03) reference 1.20 (0.91–1.57)
 Model 4 0.89 (0.77–1.03) reference 1.19 (0.90–1.57)
 Sensitivity analysis* 0.89 (0.77–1.04) reference 1.19 (0.90–1.57)
women
 Cases (%) 25 (2.26) 224 (1.24) 5 (1.33)
  Model 1 1.13 (0.74–1.72) reference 1.60 (0.66–3.91)
  Model 2 1.11 (0.72–1.69) reference 1.64 (0.67–4.00)
  Model3§ 1.05 (0.68–1.61) reference 1.31 (0.54–3.21)
  Model 4 1.05 (0.68–1.61) reference 1.30 (0.53–3.18)
  Sensitivity analysis* 1.01 (0.65–1.58) reference 1.38 (0.56–3.36)
men
 Cases (%) 185 (3.34) 2016 (2.93) 49 (4.02)
  Model 1 0.91 (0.78–1.06) reference 1.29 (0.97–1.72)
  Model 2 0.90 (0.77–1.05) reference 1.28 (0.97–1.71)
  Model 3§ 0.88 (0.75–1.02) reference 1.20 (0.90–1.60)
  Model 4 0.87 (0.74–1.02) reference 1.19 (0.90–1.59)
  Sensitivity analysis* 0.88 (0.75–1.03) reference 1.18 (0.88–1.59)

CI, confidence interval.

Model 1 was stratified by hospitals, and adjusted for age and sex.

Model 2 was stratified by hospitals, and adjusted for as model 1 plus marital status, family per member monthly income, education level, smoking status, drinking status, physical activity, and family history of stroke.

§Model 3 was stratified by hospitals, and adjusted for the variables in Model 2 plus body mass index, systolic blood pressure, diastolic blood pressure, fasting blood glucose, total cholesterol, hypotensive drug use, lipid-lowering drug use, hypoglycemic drug use, history of myocardial infarction, and snoring status.

Model 4 was stratified by hospitals, and adjusted for the variables in Model 3 plus high sensitive C-reactive protein, and atrial fibrillation.

*Adjusted for model 3 and further excluded individuals with myocardial infarction and cancer.