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. 2016 Sep 16;6:33039. doi: 10.1038/srep33039

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Copyright © 2016, The Author(s)

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(A,B) Comparative analysis of 22 DUB mRNA levels in HBxΔ35-overexpressing LO2 (A) and HepG2 (B) cells relative to mRNA levels in control cells. (C) The log2 values (fold change) for both LO2 and HepG2 were plotted. (D,E) USP16 expression levels regulated by HBxΔ35 were examined using real-time PCR (D) and western blot (E) analysis in LO2, HepG2, Huh7 and PLC/PRF/5 cells. (F) The expression levels of USP16 regulated by HBxΔ14 were examined by western blot in LO2 and HepG2 cells. The data represent the mean ± S.D, *p < 0.05, **p < 0.01, determined by t-test.