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. 2016 Sep 16;6:33453. doi: 10.1038/srep33453

Table 1. Physical and biochemical findings in blood plasma amongst different experimental groups.

  TAA (n = 8) TAA + OCA (n = 9) P-value TAA + 4 (n = 6) TAA + 4 + OCA (n = 9) P-value
Body weight (g) 319 ± 11 302 ± 11 0.27 395 ± 9 410 ± 12 0.38
Overall average dose TAA (g/L) 520 ± 13 478 ± 23 0.15 478 ± 19 450 ± 21 0.31
Liver weight 22 ± 2 22 ± 2 0.89 24 ± 2 22 ± 2 0.32
Albumin (g/L) 33.5 ± 0.8 35.1 ± 1.2 0.28 35.2 ± 1.0 36.6 ± 0.7 0.45
AST (IU/L) 85 ± 4 87 ± 7 0.76 100 ± 4 93 ± 4 0.68
ALT (IU/L) 75 ± 4 66 ± 3 0.34 97 ± 4 79 ± 4 *0.01
Bilirubin (mg/dL) 0.3 ± 0.1 0.3 ± 0.2 0.92 0.0 ± 0.0 0.0 ± 0.1 0.90

TAA, thioacetamide; OCA, obeticholic acid; AST, aspartate aminotransferase; ALT, alanine aminotransferase.